الرئيسية / الفعاليات العلمية / Pheromonal compounds and histological alteration of castrated mouse preputial gland in relation to eruca sativa extract

Pheromonal compounds and histological alteration of castrated mouse preputial gland in relation to eruca sativa extract

M. H. Homady* and A. A. Majeed
Department of Biology, Faculty of Science, Kufa University, AL-Najef, 54001, Iraq.
*e-mail: merzahh@yahoo.com
(Accepted 10 October 2017)
ABSTRACT : The effects of 3mg/kg/day of Eruca sativa on melanocortin-5-recepter (MC5R); total lipid compounds,
essential pheromonal compounds and the histological structure of the castrated male mice preputial glands for 42 days
of treatment were investigated.This treatment is resulted in a significant increase of MC5R level in preputial gland as
compared with the control (P<0.01).Also such treatment has marked effects on the total volatile lipid compounds (only
26 compounds appeared out of 55). Additionally this treatment was able to restore four compounds of the essential
pheromones which are (
α-Farnesene and (E)-α-Farnesene); (1-Tetradecanol); (Tetradecanol, acetate) and (1-Hexadecanol,
acetate). Histological sections of mouse preputial glands from castrated subjects treated with
Eruca sativa revealed that
the gland was well developed with acini at different stages of maturation.
Key words : Eruca sativa, acini, melanocortin, pheromone, histology.

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