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Master’s thesis in the Department of Biology on Immunological and Genetic Factors in Lung Cancer Patients

A master’s thesis in the Department of Biology focused on the evaluation of some immunological factors and the identification of bacterial co-infection in patients with lung cancer.

The thesis, presented by Aqil Wadi Nomi, under the supervision of Prof. Dr. Mayada Farhan Darwish, aimed to know the effect of genetic variation of cytokines on cancer and to identify the protective genes and the most dangerous genes for predicting the disease and its severity.

The results of the study showed an increase in the mean of interleukin-17, interleukin-10 and interferon-gamma in lung cancer patients, and the increase was directly correlated with the severity of the disease and with the advanced stages of the disease. Regarding the case of  non-small cell lung cancer patients, the concentration of interleukin-10 and interleukin-17 was responsible for the continuation of the inflammatory state. The latter was significantly higher than small cell lung cancer patients, and the results showed that some genes are considered risk factors, while others are protective factors.

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