Effect of Toxoplasma gondii infection on the level of NLRP3 in women with Polycystic Ovary Syndrome

Hanaa Saheb Jawad1 and Sukayna Jabbar Mushattat2*
1Altoosi university college, Department of medical Laboratories
Techniques
2University of Kufa, Faculty of Science, Department of Biology
*Corresponding author:
Sukaynaj. alhasnawee@uokufa. edu. iq
Abstract
In this study, 120 women were assessed and split into four different
categories. The first group included women who had
been exposed to the T. gondii parasite. The second group included
women possibly infected with the T. gondii parasite and
PCOS. The third group was made up of women who had PCOS.
The first three groups were hospitalized, while the fourth group
was healthy. Blood was drawn from all groups, serum was isolated,
and the level of NLRP3 was measured for all groups. The
present investigation displayed that the concentration of NLRP3
in women infected with T. gondii parasite and polycystic syndrome
increased significantly (P<0.05) (0.2250 + 6.698 ng/ml)
compared to women infected with polycystic ovary syndrome
(0.2141 +5.114 ng/ml) and women infected with the parasite
(0.2200 + 0.2200). 5.255 ng/ml) compared with the control
group (0.1065 + 2.021 ng/ml). This significant increase in the
level of concentration NLRP3 (0.2250 + 6.698 ng/ml) in women
infected with T. gondii parasite and polycystic syndrome can
be adopted as an indicator of co-prepayment, or it may be
dependent as an indicator of the occurrence of polycystic ovary
syndrome due to prior infection with the parasite.
Keywords
Toxoplasma, T. gondii parasite, Polycystic, Ovary Syndrome

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